In cautarea fericirii

Sayantani Ghosh/Aneesha Kapoor ... Kakul Shankar Chaudhary
Anisha Kapur ... Damini (look-alike of Kakul)
Ujjwal Rana/Ankur Nayyar ... Samman Chaudhary (Kakul's husband)
Alok Nath ... Amarnath Chaudhary (Samman's father)
Himani Shivpuri ... Uttara (Amarnath's wife)
Shammi Aunti .... Dadima (Amarnath's mother)
Harsh Chhaya ... Dr. Rishabh (Samman's older brother)
Lata Sabharwal ... Cynthia (Rishabh's first wife, killed in a car accident)
... Bunty (Dr. Rishabh and Cynthia's son)
Niki Walia ... Simi Ahuja (lawyer, Dr. Rishabh's friend and second wife)
Chinky Jaiswall ... Sonia Ahuja (Simi Ahuja's daughter)
Barkha Madan ... Devika (Samman's sister, later Sujeet's wife)
Vinod Singh ... Vicky (Devika's boyfriend, now dead)
Vindhya Tiwari ... Mrittika (Samman's sister, now dead) episodes 2–74, episodes 210–233
Jeetu Malkani ... Ahaan (in love with Mritika) episodes 205–231
Jaya Binju ... Tulika (Samman's sister)
Sachal Tyagi ... Abhi (son of Nana, Tulika's boyfriend)
Nagesh Bhosle ... Nana (best friend of Sujeet and Om Shankar)
Piyush Sahdev/Hasan Zaidi ... Sharad
Upsana Shukla .... Neha(Sharad's wife)
Darshan Dave ... Sujeet (Trisha's husband)
Resham Tipnis ... Trisha (Kakul's older sister, died in childbirth)
Vineet Kumar ... Om Shankar (Sujeet and Samman's father-in-law, Trisha and Kakul's father)
Varun Badola ... Gautam (Vanshika's hushand)
Aarzoo Govitrikar ... Vanshika (Samman's ex-girlfriend)
Mehul Buch ... Dhanraj Saxena (Vanshika and Neha's father, Gautam's father-in-law)
Mahesh Shetty ... Shlok Verma (stepbrother of Sharad and Mrittika, brother of Ansh)
Ali Merchant ... Ansh Verma (Shlok's younger brother, killed by him)